4IAE
Crystal structure of BAY 60-2770 bound to nostoc H-NOX domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Alr2278 protein | polymer | 189 | 21181.6 | 2 | UniProt (Q8YUQ7) Pfam (PF07700) In PDB | Nostoc sp. | |
| 2 | A, B | 4-({(4-carboxybutyl)[2-(5-fluoro-2-{[4'-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]amino}methyl)benzoic acid | non-polymer | 623.6 | 2 | Chemie (1DX) | |||
| 3 | A, B | MALONATE ION | non-polymer | 102.0 | 3 | Chemie (MLI) | |||
| 4 | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 189 (UniProt: Q8YUQ7)
| PDB | External Database | Details |
|---|---|---|
| Ala 139 | Cys 139 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42363.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1553.4 | |
| All* | Total formula weight | 43916.6 |
