4IAC

X-RAY structure of cAMP dependent protein kinase A in complex with HIGH MG2+ concentration, AMP-PCP AND pseudo-substrate peptide SP20

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	cAMP-dependent protein kinase catalytic subunit alpha	polymer	356	41566.2	1	UniProt (P05132) Pfam (PF00069) In PDB	Mus musculus (mouse)	PKA C-alpha
2	S	Peptide SP20	polymer	20	2199.4	1	UniProt (by SIFTS) (P61925) In PDB	Homo sapiens
3	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
5		water	water		18.0	339	Chemie (HOH)

Sequence modifications

A: 1 - 350 (UniProt: P05132)

PDB	External Database	Details
His -5	-	EXPRESSION TAG
His -4	-	EXPRESSION TAG
His -3	-	EXPRESSION TAG
His -2	-	EXPRESSION TAG
His -1	-	EXPRESSION TAG
His 0	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43765.6
Non-Polymers*	Number of molecules	3
	Total formula weight	553.8
All*	Total formula weight	44319.4

*Water molecules are not included.