4IAC
X-RAY structure of cAMP dependent protein kinase A in complex with HIGH MG2+ concentration, AMP-PCP AND pseudo-substrate peptide SP20
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 356 | 41566.2 | 1 | UniProt (P05132) Pfam (PF00069) | Mus musculus (mouse) | PKA C-alpha |
| 2 | B (S) | Peptide SP20 | polymer | 20 | 2199.4 | 1 | UniProt (by SIFTS) (P61925) | Homo sapiens | |
| 3 | C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E (A) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 5 | F, G (A, S) | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A: 1 - 350 (UniProt: P05132)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43765.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 553.8 | |
| All* | Total formula weight | 44319.4 |
