4I9S
Crystal Structure of the R111K:R132L:Y134F:T54V:R59W Mutant of the Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans Retinal at 2.58 Angstrom Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15520.8 | 1 | UniProt (P29373) Pfam (PF00061) | Homo sapiens (human) | Cellular retinoic acid-binding protein II, CRABP-II |
| 2 | B (A) | RETINAL | non-polymer | 284.4 | 1 | Chemie (RET) PubChem (1070) PubChem (23254473) PubChem (177675058) PubChem (638015) PubChem (5353924) PubChem (6436079) PubChem (6436082) PubChem (87082476) PubChem (87110449) PubChem (87110609) PubChem (88398773) PubChem (88407543) PubChem (11426127) PubChem (12227253) PubChem (12227254) PubChem (12227256) PubChem (12227257) PubChem (12227258) PubChem (12227259) PubChem (12227269) PubChem (12227270) PubChem (12227271) PubChem (5280490) PubChem (5381765) PubChem (134688327) PubChem (140510408) PubChem (145826762) PubChem (169423542) PubChem (172878320) | |||
| 3 | C (A) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 1 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Val 54 | Thr 55 | engineered mutation |
| Trp 59 | Arg 60 | engineered mutation |
| Lys 111 | Arg 112 | engineered mutation |
| Leu 132 | Arg 133 | engineered mutation |
| Phe 134 | Tyr 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15520.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 284.4 | |
| All* | Total formula weight | 15805.2 |
