4I9L
Crystal structure of the D714A mutant of RB69 DNA polymerase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase | polymer | 903 | 104611.1 | 1 | UniProt (Q38087) Pfam (PF03104) Pfam (PF00136) | Enterobacteria phage RB69 | Gp43 |
| 2 | B (A) | GUANOSINE | non-polymer | 283.2 | 1 | Chemie (GMP) PubChem (135499520) PubChem (162360751) PubChem (135398635) PubChem (135402034) PubChem (135426840) PubChem (135440077) PubChem (135484501) PubChem (135508725) PubChem (135514572) PubChem (135538738) PubChem (135546397) PubChem (135699331) PubChem (135726185) PubChem (135768161) PubChem (135768162) PubChem (135796591) PubChem (135823787) PubChem (135976484) PubChem (136019960) PubChem (136029099) PubChem (136029343) PubChem (136032217) PubChem (136073062) PubChem (136073540) PubChem (136168113) PubChem (136200123) PubChem (136259572) PubChem (136263240) PubChem (136461600) PubChem (136474462) PubChem (136490162) PubChem (136594098) PubChem (136596777) PubChem (136612256) PubChem (136614128) PubChem (136835877) PubChem (136912867) PubChem (136996824) PubChem (137506101) PubChem (163824507) PubChem (166857379) PubChem (168265885) PubChem (173984522) | |||
| 3 | C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F, G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 5 | I (A) | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A: 1 - 903 (UniProt: Q38087)
| PDB | External Database | Details |
|---|---|---|
| Ala 222 | Asp 222 | engineered mutation |
| Ala 327 | Asp 327 | engineered mutation |
| Ala 714 | Asp 714 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 104611.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 677.8 | |
| All* | Total formula weight | 105288.9 |
