4I8Z

Crystal structure of wild type HIV-1 protease in complex with non-peptidic inhibitor, GRL008

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protease	polymer	99	10803.8	2	UniProt (P0C6F2) Pfam (PF00077) In PDB	Human immunodeficiency virus type 1 (HIV-1)
2	A	(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-carbamoylphenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate	non-polymer		575.7	1	Chemie (G08)
3		water	water		18.0	128	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21607.5
Non-Polymers*	Number of molecules	1
	Total formula weight	575.7
All*	Total formula weight	22183.2

*Water molecules are not included.