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4I6W

3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
3-hydroxy-3-methylglutaryl-coenzyme A reductasepolymer42845641.22UniProt (P13702)
Pfam (PF00368)
Pseudomonas mevaloniiHMG-CoA reductase
2C, G
(A, B)
(3S)-3-hydroxy-3-methyl-5-sulfanylpentanoic acidnon-polymer164.22Chemie (1CO)
3D, E, H, I
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
4F, J
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
5K, L
(A, B)
waterwater18.0701Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight91282.5
Non-Polymers*Number of molecules8
Total formula weight896.9
All*Total formula weight92179.4
*Water molecules are not included.

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PDB entries from 2025-12-03

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