4I68
Crystal structure of the R444A / R449A double mutant of the HERA RNA helicase RRM domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat resistant RNA dependent ATPase | polymer | 90 | 9665.1 | 1 | UniProt (Q72GF3) Pfam (PF22231) | Thermus thermophilus | HERA RNA helicase |
| 2 | B, C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 3 | E, F, G (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | H (A) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A: 424 - 510 (UniProt: Q72GF3)
| PDB | External Database | Details |
|---|---|---|
| Gly 421 | - | expression tag |
| Ala 422 | - | expression tag |
| Met 423 | - | expression tag |
| Ala 444 | Arg 451 | engineered mutation |
| Ala 449 | Arg 456 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 9665.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 302.6 | |
| All* | Total formula weight | 9967.7 |
