4I4B
HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate hemiacetal form of HMG-CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | polymer | 428 | 45641.2 | 2 | UniProt (P13702) Pfam (PF00368) | Pseudomonas mevalonii | HMG-CoA reductase |
| 2 | C (A) | (3R,5R,9R,19R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8,21-trimethyl-10,14-dioxo-19-sulfanyl-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide | non-polymer | 929.7 | 1 | Chemie (1CV) | |||
| 3 | D, H, I (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | F (B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 6 | G (B) | (3S)-3-hydroxy-3-methyl-5-sulfanylpentanoic acid | non-polymer | 164.2 | 1 | Chemie (1CO) | |||
| 7 | J, K (A, B) | water | water | 18.0 | 755 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91282.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2129.7 | |
| All* | Total formula weight | 93412.2 |
