4I0X
Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | ESAT-6-like protein MAB_3112 | polymer | 94 | 9796.5 | 6 | UniProt (B1MD68) Pfam (PF06013) | Mycobacterium abscessus | |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | ESAT-6-like protein MAB_3113 | polymer | 103 | 11427.5 | 6 | UniProt (B1MD69) Pfam (PF06013) | Mycobacterium abscessus | |
| 3 | M (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | N (B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 5 | O (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | AA, P, Q, R, S... (L, A, B, C, D...) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K: 1 - 93 (UniProt: B1MD68)
B, D, F, H, J, L: 1 - 103 (UniProt: B1MD69)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Asn 23 | Ser 35 | engineered mutation |
| Lys 37 | Arg 49 | engineered mutation |
| Ala 75 | Val 87 | engineered mutation |
| Asp 93 | Gly 105 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Pro 2 | engineered mutation |
| Ala 51 | Thr 51 | engineered mutation |
| Gln 60 | Glu 60 | engineered mutation |
| Ser 77 | Asn 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 127344.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 266.3 | |
| All* | Total formula weight | 127610.6 |
