4I0X
Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G, I... | ESAT-6-like protein MAB_3112 | polymer | 94 | 9796.5 | 6 | UniProt (B1MD68) Pfam (PF06013) In PDB | Mycobacterium abscessus | |
2 | B, D, F, H, J... | ESAT-6-like protein MAB_3113 | polymer | 103 | 11427.5 | 6 | UniProt (B1MD69) Pfam (PF06013) In PDB | Mycobacterium abscessus | |
3 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
5 | C | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K: 1 - 93 (UniProt: B1MD68)
B, D, F, H, J, L: 1 - 103 (UniProt: B1MD69)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
Asn 23 | Ser 35 | engineered mutation |
Lys 37 | Arg 49 | engineered mutation |
Ala 75 | Val 87 | engineered mutation |
Asp 93 | Gly 105 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 2 | Pro 2 | engineered mutation |
Ala 51 | Thr 51 | engineered mutation |
Gln 60 | Glu 60 | engineered mutation |
Ser 77 | Asn 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 127344.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 266.3 | |
All* | Total formula weight | 127610.6 |