4HZN

The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Bifunctional Methylmalonyl-CoA:ACP Acyltransferase/Decarboxylase	polymer	333	37378.8	1	UniProt (Q8GGP1)	Streptomyces atroolivaceus
2	B (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	D, E, F, G, H (A)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
5	I (A)	water	water		18.0	113	Chemie (HOH)

Sequence modifications

A: 1 - 319 (UniProt: Q8GGP1)

PDB	External Database	Details
Mse -13	-	expression tag
Ala -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Val -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37378.8
Non-Polymers*	Number of molecules	7
	Total formula weight	694.6
All*	Total formula weight	38073.4

*Water molecules are not included.