4HZH
Structure of recombinant Gla-domainless prothrombin mutant S525A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prothrombin | polymer | 533 | 60115.4 | 2 | UniProt (P00734) Pfam (PF00051) Pfam (PF09396) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain |
| 2 | C, D, E, F (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A, B: 47 - 579 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 525 | Ser 568 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120230.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 121115.6 |
