4HYI
X-RAY Crystal structure of compound 40 bound to human chk1 kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Chk1 | polymer | 289 | 33043.0 | 1 | UniProt (O14757) Pfam (PF00069) | Homo sapiens (human) | CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1 |
| 2 | B, C, D (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | E (A) | 2-(1H-indazol-1-yl)-N-[2-(piperazin-1-yl)phenyl]-1,3-thiazole-4-carboxamide | non-polymer | 404.5 | 1 | Chemie (1AO) | |||
| 4 | F (A) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33043.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 680.8 | |
| All* | Total formula weight | 33723.8 |
