4HXI
Crystal structure of KLHL3/Cul3 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Kelch-like protein 3 | polymer | 277 | 31366.8 | 1 | UniProt (Q9UH77) Pfam (PF00651) Pfam (PF07707) In PDB | Homo sapiens (human) | |
| 2 | B | Cullin-3 | polymer | 386 | 45209.7 | 1 | UniProt (Q13618) Pfam (PF00888) In PDB | Homo sapiens (human) | CUL-3 |
Sequence modifications
A: 24 - 276 (UniProt: Q9UH77)
B: 20 - 381 (UniProt: Q13618)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| Ser 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Gly 9 | - | expression tag |
| Val 10 | - | expression tag |
| Asp 11 | - | expression tag |
| Leu 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Thr 14 | - | expression tag |
| Glu 15 | - | expression tag |
| Asn 16 | - | expression tag |
| Leu 17 | - | expression tag |
| Tyr 18 | - | expression tag |
| Phe 19 | - | expression tag |
| Gln 20 | - | expression tag |
| Ser 21 | - | expression tag |
| Asn 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Ala 87 | Lys 87 | engineered mutation |
| Ala 89 | Lys 89 | engineered mutation |
| Ala 90 | Lys 90 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -23 | - | expression tag |
| Leu -22 | - | expression tag |
| Asn -21 | - | expression tag |
| Asp -20 | - | expression tag |
| Ile -19 | - | expression tag |
| Phe -18 | - | expression tag |
| Glu -17 | - | expression tag |
| Ala -16 | - | expression tag |
| Gln -15 | - | expression tag |
| Lys -14 | - | expression tag |
| Ile -13 | - | expression tag |
| Glu -12 | - | expression tag |
| Trp -11 | - | expression tag |
| His -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Ala -8 | - | expression tag |
| Met -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Arg 274 | Lys 274 | engineered mutation |
| Arg 342 | Ile 342 | engineered mutation |
| Asp 346 | Leu 346 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76576.5 | |
| All* | Total formula weight | 76576.5 |
