4HXD
Diversity of ubiquitin and ISG15 specificity amongst nairoviruses viral ovarian tumor domain proteases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Polyubiquitin-C | polymer | 75 | 8519.8 | 2 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | Ubiquitin |
| 2 | B, D (B, D) | RNA-directed RNA polymerase L | polymer | 174 | 20011.4 | 2 | UniProt (Q66431) Pfam (PF02338) | Dugbe virus (isolate ArD44313) (DUGV) | Protein L, Large structural protein, Replicase, Transcriptase, Ubiquitin thioesterase, RNA-directed RNA polymerase |
| 3 | E, G (A, C) | 1.7.6 3-bromanylpropan-1-amine | non-polymer | 138.0 | 2 | Chemie (4LJ) | |||
| 4 | F, H, I (A, C, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
B, D: 2 - 169 (UniProt: Q66431)
| PDB | External Database | Details |
|---|---|---|
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
| His 174 | - | expression tag |
| His 175 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57062.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 564.2 | |
| All* | Total formula weight | 57626.6 |
