4HXD

Diversity of ubiquitin and ISG15 specificity amongst nairoviruses viral ovarian tumor domain proteases

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Polyubiquitin-C	polymer	75	8519.8	2	UniProt (P0CG48) Pfam (PF00240) In PDB	Homo sapiens (human)	Ubiquitin
2	B, D	RNA-directed RNA polymerase L	polymer	174	20011.4	2	UniProt (Q66431) Pfam (PF02338) In PDB	Dugbe virus (isolate ArD44313) (DUGV)	Protein L, Large structural protein, Replicase, Transcriptase, Ubiquitin thioesterase, RNA-directed RNA polymerase
3	A, C	1.7.6 3-bromanylpropan-1-amine	non-polymer		138.0	2	Chemie (4LJ)
4	A, C, D	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5		water	water		18.0	46	Chemie (HOH)

Sequence modifications

B, D: 2 - 169 (UniProt: Q66431)

PDB	External Database	Details
His 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	57062.4
Non-Polymers*	Number of molecules	5
	Total formula weight	564.2
All*	Total formula weight	57626.6

*Water molecules are not included.