4HX1
Structure of HLA-A68 complexed with a tumor antigen derived peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I antigen | polymer | 274 | 31778.1 | 1 | UniProt (Q1ELT0) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C (C) | 9-mer peptide from Tyrosinase-related protein-2 | polymer | 9 | 1175.3 | 1 | UniProt (O75767) UniProt (by SIFTS) (P40126) | Homo sapiens | tumor antigen derived peptide |
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F, G (A, B, C) | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence modifications
A: 1 - 274 (UniProt: Q1ELT0)
| PDB | External Database | Details |
|---|---|---|
| Lys 273 | Arg 297 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44701.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 44793.7 |
