4HUG

Structure of 5-chlorouracil modified A:U base pairs

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ribonuclease H	polymer	134	15429.4	2	UniProt (Q9KEI9) In PDB	Bacillus halodurans	RNase H
2	C, D, E, F	DNA (5'-D(*CP*GP*CP*GP*AP*AP*(UCL)P*(UCL)P*CP*GP*CP*G)-3')	polymer	12	3704.2	4
3	A, E	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	B, D	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	E, F	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6		water	water		18.0	428	Chemie (HOH)

Sequence modifications

A, B: 61 - 194 (UniProt: Q9KEI9)

PDB	External Database	Details
Asn 132	Asp 132	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	45675.7
Non-Polymers*	Number of molecules	6
	Total formula weight	356.9
All*	Total formula weight	46032.6

*Water molecules are not included.