4HQR

Crystal Structure of mutant form of Caspase-7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Caspase-7	polymer	272	31013.3	2	UniProt (P55210) Pfam (PF00656)	Homo sapiens (human)
2	C, D (E, F)	Ac-Asp-Glu-Val-Asp-Aldehyde	polymer	5	488.5	2	BIRD (PRD_000422)

Sequence modifications

A, B: 47 - 303 (UniProt: P55210)

PDB	External Database	Details
Met 46	-	expression tag
Ala 198	Asp 198	engineered mutation
Leu 204	-	insertion
Val 204	-	insertion
Pro 204	-	insertion
Arg 204	-	insertion
Gly 204	-	insertion
Ser 204	-	insertion
Leu 304	-	expression tag
Glu 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	63003.6
All*	Total formula weight	63003.6

*Water molecules are not included.