4HP1

Crystal structure of Tet3 in complex with a non-CpG dsDNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA (5'-D(*GP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*C)-3')	polymer	12	3678.4	2
2	C (C)	LOC100036628 protein	polymer	72	8430.0	1	UniProt (A0JP82) Pfam (PF02008)	Xenopus (Silurana) tropicalis (Western clawed frog)
3	D, E (C)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	F, G, H (A, B, C)	water	water		18.0	10	Chemie (HOH)

Sequence modifications

C: 58 - 111 (UniProt: A0JP82)

PDB	External Database	Details
Met 40	-	expression tag
His 41	-	expression tag
His 42	-	expression tag
His 43	-	expression tag
His 44	-	expression tag
His 45	-	expression tag
His 46	-	expression tag
Ser 47	-	expression tag
Ser 48	-	expression tag
Gly 49	-	expression tag
Arg 50	-	expression tag
Glu 51	-	expression tag
Asn 52	-	expression tag
Leu 53	-	expression tag
Tyr 54	-	expression tag
Phe 55	-	expression tag
Gln 56	-	expression tag
Gly 57	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	15786.9
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	15917.7

*Water molecules are not included.