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4HOM

Crystal structure of porcine aminopeptidase-N complexed with substance P

Replaces:  4FKN
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Aminopeptidase Npolymer908103521.21UniProt (P15145)
Pfam (PF17900)
Pfam (PF01433)
Pfam (PF11838)
Sus scrofa (pig)AP-N, pAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Microsomal aminopeptidase, gp130
2B
(B)
substance Ppolymer111350.61Pfam (PF02202)
UniProt (by SIFTS) (P20366)
3C, D, G
(C, D, G)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched627.63In PDB
BIRD (PRD_900017)
GlyTouCan (G47362BJ)
triacetyl-beta-chitotriose
4E, F, H, I, J...
(E, F, H, I, J...)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.46In PDB
GlyTouCan (G42666HT)
5L, M
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
6N
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
7O, P
(A, B)
waterwater18.01434Chemie (HOH)
Sequence modifications
A: 63 - 963 (UniProt: P15145)
PDBExternal DatabaseDetails
Asn 82Phe 82conflict
Phe 107Leu 107conflict
Ser 964-expression tag
His 965-expression tag
His 966-expression tag
His 967-expression tag
His 968-expression tag
His 969-expression tag
His 970-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight104871.8
BranchedNumber of molecules9
Total formula weight4429.2
Non-Polymers*Number of molecules3
Total formula weight507.8
All*Total formula weight109808.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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