4HNJ
Crystallographic structure of BCL-xL domain-swapped dimer in complex with PUMA BH3 peptide at 2.9A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bcl-2-like protein 1 | polymer | 212 | 23669.9 | 2 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | Bcl2-L-1, Apoptosis regulator Bcl-X |
2 | C | Bcl-2-binding component 3 | polymer | 25 | 3053.3 | 1 | UniProt (Q9BXH1) In PDB | Homo sapiens | JFY-1, p53 up-regulated modulator of apoptosis |
3 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 209 (UniProt: Q07817)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 50393.2 | |
All* | Total formula weight | 50393.2 |