4HNJ
Crystallographic structure of BCL-xL domain-swapped dimer in complex with PUMA BH3 peptide at 2.9A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bcl-2-like protein 1 | polymer | 212 | 23669.9 | 2 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) | Homo sapiens (human) | Bcl2-L-1, Apoptosis regulator Bcl-X |
| 2 | C (C) | Bcl-2-binding component 3 | polymer | 25 | 3053.3 | 1 | UniProt (Q9BXH1) | Homo sapiens | JFY-1, p53 up-regulated modulator of apoptosis |
| 3 | D, E (A, C) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 209 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50393.2 | |
| All* | Total formula weight | 50393.2 |
