4HLA

Crystal structure of wild type HIV-1 protease in complex with darunavir

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protease	polymer	99	10803.8	2	UniProt (P03367) Pfam (PF00077) In PDB	Human immunodeficiency virus type 1 (BRU ISOLATE) (HIV-1)	Pr160Gag-Pol
2	A	(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE	non-polymer		547.7	1	Chemie (017)
3		water	water		18.0	196	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21607.5
Non-Polymers*	Number of molecules	1
	Total formula weight	547.7
All*	Total formula weight	22155.2

*Water molecules are not included.