4HKS
Calcium release-activated calcium (CRAC) channel ORAI, K163W mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Calcium release-activated calcium channel protein 1 | polymer | 214 | 24404.4 | 2 | UniProt (Q9U6B8) Pfam (PF07856) | Drosophila melanogaster (Fruit fly) | Protein orai, dOrai |
| 2 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A, B: 133 - 341 (UniProt: Q9U6B8)
| PDB | External Database | Details |
|---|---|---|
| Trp 163 | Lys 163 | engineered mutation |
| Ser 224 | Cys 224 | engineered mutation |
| Arg 276 | Pro 276 | engineered mutation |
| Arg 277 | Pro 277 | engineered mutation |
| Thr 283 | Cys 283 | engineered mutation |
| Glu 342 | - | expression tag |
| Gly 343 | - | expression tag |
| Glu 344 | - | expression tag |
| Glu 345 | - | expression tag |
| Phe 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48808.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 105.5 | |
| All* | Total formula weight | 48914.3 |
