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4HKI

Tankyrase 2 in complex with flavone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, H)
Tankyrase-2polymer19121824.52UniProt (Q9H2K2)
Pfam (PF00644)
Homo sapiens (human)TANK2, ADP-ribosyltransferase diphtheria toxin-like 6, ARTD6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein
2B, D
(C, D)
Tankyrase-2polymer495493.22UniProt (Q9H2K2)Homo sapiens (human)
3E, K
(A, H)
ZINC IONnon-polymer65.42Chemie (ZN)
4F, G, L, M
(A, H)
SULFATE IONnon-polymer96.14Chemie (SO4)
5H, N
(A, H)
2-PHENYL-4H-CHROMEN-4-ONEnon-polymer222.22Chemie (FLN)
6I, O
(C, H)
GLYCEROLnon-polymer92.12Chemie (GOL)
7J, P
(C, H)
DI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
8Q, R, S, T
(A, C, H, D)
waterwater18.0210Chemie (HOH)
Sequence modifications
A, H: 946 - 1113 (UniProt: Q9H2K2)
PDBExternal DatabaseDetails
Met 923-expression tag
His 924-expression tag
His 925-expression tag
His 926-expression tag
His 927-expression tag
His 928-expression tag
His 929-expression tag
Ser 930-expression tag
Ser 931-expression tag
Gly 932-expression tag
Val 933-expression tag
Asp 934-expression tag
Leu 935-expression tag
Gly 936-expression tag
Thr 937-expression tag
Glu 938-expression tag
Asn 939-expression tag
Leu 940-expression tag
Tyr 941-expression tag
Phe 942-expression tag
Gln 943-expression tag
Ser 944-expression tag
Met 945-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight54635.5
Non-Polymers*Number of molecules12
Total formula weight1356.0
All*Total formula weight55991.5
*Water molecules are not included.

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PDB entries from 2024-11-20

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