4HJT

Kinetic stabilization of transthyretin through covalent modification of K15 by (E)-N-(4-(4-hydroxy-3,5-dimethylstyryl)phenyl)propionamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transthyretin	polymer	127	13777.4	2	UniProt (P02766) Pfam (PF00576)	Homo sapiens (human)	ATTR, Prealbumin, TBPA
2	C, D (A, B)	N-{4-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]phenyl}propanamide	non-polymer		295.4	2	Chemie (18A)
3	E, F (A, B)	water	water		18.0	82	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27554.7
Non-Polymers*	Number of molecules	2
	Total formula weight	590.8
All*	Total formula weight	28145.5

*Water molecules are not included.