4HJE

Crystal structure of p53 core domain in complex with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Cellular tumor antigen p53	polymer	200	22529.6	4	UniProt (P04637) Pfam (PF00870)	Homo sapiens (human)	Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
2	E (E)	DNA (5'-D(*TP*CP*AP*CP*AP*AP*GP*TP*TP*AP*GP*AP*GP*AP*CP*AP*AP*GP*CP*CP*T)-3')	polymer	21	6440.2	1
3	F (F)	DNA (5'-D(*AP*GP*GP*CP*TP*TP*GP*TP*CP*TP*CP*TP*AP*AP*CP*TP*TP*GP*TP*GP*A)-3')	polymer	21	6444.2	1
4	G, H, I, J (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	832	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	103002.9
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	103264.5

*Water molecules are not included.