4HI3

Crystal structure of dimeric R298A mutant of SARS coronavirus main protease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	3C-like proteinase	polymer	315	34992.9	2	UniProt (P0C6U8) Pfam (PF05409) In PDB	SARS coronavirus	3CL-PRO, 3CLp
2		water	water		18.0	266	Chemie (HOH)

Sequence modifications

A, B: 1 - 306 (UniProt: P0C6U8)

PDB	External Database	Details
Met 0	-	initiating methionine
Ala 298	Arg 3538	engineered mutation
Leu 307	-	expression tag
Glu 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69985.7
All*	Total formula weight	69985.7

*Water molecules are not included.