4HC7

Crystal structure of the full DNA binding domain of GATA3-complex 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, B)	Trans-acting T-cell-specific transcription factor GATA-3	polymer	115	12893.9	2	UniProt (P23771) Pfam (PF00320)	Homo sapiens (human)	GATA-binding factor 3
2	B, E (W, Y)	DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3')	polymer	20	6086.0	2
3	C, F (X, Z)	DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3')	polymer	20	6179.0	2
4	G, H, I, J (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	K, L, M, N, O... (A, W, X, B, Y...)	water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, B: 261 - 371 (UniProt: P23771)

PDB	External Database	Details
Gly 257	-	expression tag
Ser 258	-	expression tag
His 259	-	expression tag
Met 260	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	50317.7
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	50579.4

*Water molecules are not included.