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4HBU

Crystal structure of CTX-M-15 extended-spectrum beta-lactamase in complex with avibactam (NXL104)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ABeta-lactamasepolymer26328138.81UniProt (Q9EXV5)
Pfam (PF00144)
Pfam (PF13354)
In PDB
Escherichia coliBeta-lactamase CTX-M, Beta-lactamase CTX-M-15, Beta-lactamase bla-CTX-M-15, BlaCTX-M-15, CTX-M-15, CTX-M-15 beta-lactamase, CTX-M-15 extended-spectrum beta-lactamase, CTX-m-3-like beta-lactamase, Extended-spectrum beta-lactamase CTX-M-15
2A(2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamidenon-polymer267.31Chemie (NXL)
3A1,2-ETHANEDIOLnon-polymer62.110Chemie (EDO)
4ACHLORIDE IONnon-polymer35.51Chemie (CL)
5ASULFATE IONnon-polymer96.14Chemie (SO4)
6waterwater18.0312Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28138.8
Non-Polymers*Number of molecules16
Total formula weight1307.6
All*Total formula weight29446.5
*Water molecules are not included.

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PDB entries from 2024-08-28

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