4H97
Candida albicans dihydrofolate reductase complexed with NADPH and 5-{3-[3-methoxy-5-(4-methylphenyl)phenyl]but-1-yn-1-yl}-6-methylpyrimidine-2,4-diamine (UCP111D4M)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dihydrofolate Reductase | polymer | 190 | 21950.2 | 2 | UniProt (Q5A5E0) Pfam (PF00186) UniProt (by SIFTS) (P22906) In PDB | Candida albicans | |
| 2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | A, B | 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine | non-polymer | 372.5 | 2 | Chemie (53S) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 192 (UniProt: Q5A5E0)
| PDB | External Database | Details |
|---|---|---|
| Lys 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43900.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2327.9 | |
| All* | Total formula weight | 46228.2 |
