4H95
Candida albicans dihydrofolate reductase complexed with NADPH and 6-ethyl-5-{3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine (UCP1006)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate Reductase | polymer | 189 | 21821.0 | 2 | UniProt (Q5A5E0) UniProt (by SIFTS) (P22906) | Candida albicans (Yeast) | |
| 2 | C, E (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, F (A, B) | 6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine | non-polymer | 373.5 | 2 | Chemie (06U) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43642.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2237.7 | |
| All* | Total formula weight | 45879.7 |
