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4H7X

Crystal structure of the tetratricopeptide repeat (TPR) motif of human dual specificity protein kinase Mps1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Dual specificity protein kinase TTKpolymer16118187.12UniProt (P33981)Homo sapiens (human)Phosphotyrosine picked threonine-protein kinase, PYT
2C
(A)
LEAD (II) IONnon-polymer207.21Chemie (PB)
3D, E
(A, B)
waterwater18.052Chemie (HOH)
Sequence modifications
A, B: 6 - 161 (UniProt: P33981)
PDBExternal DatabaseDetails
Gly 1-expression tag
Pro 2-expression tag
Leu 3-expression tag
Gly 4-expression tag
Ser 5-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight36374.1
Non-Polymers*Number of molecules1
Total formula weight207.2
All*Total formula weight36581.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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