4H67
Crystal structure of HMP synthase Thi5 from S. cerevisiae
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Pyrimidine precursor biosynthesis enzyme THI5 | polymer | 346 | 39329.4 | 8 | UniProt (P43534) Pfam (PF09084) In PDB | Saccharomyces cerevisiae (yeast) | HMP synthase Thi5 |
2 | A, C, D, E, F... | SULFATE ION | non-polymer | 96.1 | 17 | Chemie (SO4) | |||
3 | B | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
4 | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 340 (UniProt: P43534)
PDB | External Database | Details |
---|---|---|
Ser 240 | Lys 240 | engineered mutation |
Gly 241 | Glu 241 | engineered mutation |
Thr 317 | Gln 317 | engineered mutation |
His 341 | - | expression tag |
His 342 | - | expression tag |
His 343 | - | expression tag |
His 344 | - | expression tag |
His 345 | - | expression tag |
His 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 314634.9 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 1880.2 | |
All* | Total formula weight | 316515.1 |