4H58
BRAF in complex with compound 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Serine/threonine-protein kinase B-raf | polymer | 275 | 31351.3 | 3 | UniProt (P15056) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1 |
| 2 | D (A) | N-(4-{[(2-methoxyethyl)amino]methyl}phenyl)-6-(pyridin-4-yl)quinazolin-2-amine | non-polymer | 385.5 | 1 | Chemie (10Z) | |||
| 3 | E (C) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | F, G, H (A, B, C) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 94054.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 420.9 | |
| All* | Total formula weight | 94474.9 |
