4H1L
TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 178 | 20727.4 | 2 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | MHC class II antigen DRA |
| 2 | B, E (B, E) | MHC class II antigen | polymer | 187 | 21848.5 | 2 | UniProt (D0AB36) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P79483) | Homo sapiens (human) | |
| 3 | C, F (C, F) | mimotope peptide | polymer | 13 | 1539.8 | 2 | Escherichia coli | ||
| 4 | G, I (G, I) | Ani2.3 TCR A chain | polymer | 113 | 12426.9 | 2 | Pfam (PF07686) UniProt (by SIFTS) (L7MTK9) | Escherichia coli | |
| 5 | H, J (H, J) | Ani2.3 TCR B chain | polymer | 111 | 12634.0 | 2 | Pfam (PF07686) UniProt (by SIFTS) (L7MTL0) | Escherichia coli |
Sequence modifications
B, E: 6 - 188 (UniProt: D0AB36)
| PDB | External Database | Details |
|---|---|---|
| Arg 4 | - | expression tag |
| Pro 5 | - | expression tag |
| Gln 74 | Arg 69 | SEE REMARK 999 |
| Val 86 | Gly 81 | SEE REMARK 999 |
| Arg 189 | - | expression tag |
| Ala 190 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 138353.3 | |
| All* | Total formula weight | 138353.3 |
