4H1I

Structure of human thymidylate synthase at low salt conditions

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Thymidylate synthase	polymer	318	36453.7	4	UniProt (P04818) Pfam (PF00303)	Homo sapiens (human)	TS, TSase
2	E, F, G, H (A, C, D)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	I, J, K, L (A, B, C, D)	water	water		18.0	21	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 313 (UniProt: P04818)

PDB	External Database	Details
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	145814.7
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	146198.9

*Water molecules are not included.