4H0T
Crystal structure of Ia-ADPR-actin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Iota toxin component Ia | polymer | 418 | 48219.2 | 1 | UniProt (Q46220) | Clostridium perfringens | |
| 2 | B (B) | Actin, alpha skeletal muscle | polymer | 375 | 41862.6 | 1 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (rabbit) | Alpha-actin-1 |
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 4 | D, E, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) | |||
| 5 | M (B) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 1 | Chemie (AR6) PubChem (192) PubChem (25113622) PubChem (25113623) PubChem (44415180) PubChem (51051599) PubChem (44144391) PubChem (445794) PubChem (447048) PubChem (89379870) PubChem (33576) PubChem (447165) PubChem (448826) PubChem (91746164) PubChem (9548001) PubChem (9547960) PubChem (122606931) PubChem (122609061) PubChem (10437766) PubChem (174159053) PubChem (140853820) PubChem (146879505) PubChem (162774256) PubChem (162782217) PubChem (163972867) PubChem (173750345) PubChem (173750346) PubChem (175675949) | |||
| 6 | N (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 7 | O (B) | LATRUNCULIN A | non-polymer | 421.6 | 1 | Chemie (LAR) PubChem (20054953) PubChem (3891) PubChem (22832181) PubChem (22832298) PubChem (24816451) PubChem (24832051) PubChem (16760535) PubChem (107993) PubChem (53237841) PubChem (46936439) PubChem (445420) PubChem (57484570) PubChem (76327939) PubChem (89005581) PubChem (14133242) PubChem (70701335) PubChem (70820543) PubChem (91886139) PubChem (5353711) PubChem (5459089) PubChem (5943927) PubChem (9931975) PubChem (6437378) PubChem (10387471) PubChem (124526973) PubChem (124674678) PubChem (14133244) PubChem (162879224) PubChem (162879223) PubChem (134688496) PubChem (146159700) PubChem (162879221) PubChem (162879222) PubChem (162879225) PubChem (166640061) PubChem (168314144) | |||
| 8 | P (B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 9 | AA, Z (B, A) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A: 1 - 413 (UniProt: Q46220)
| PDB | External Database | Details |
|---|---|---|
| Arg -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90081.8 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 2740.3 | |
| All* | Total formula weight | 92822.1 |
