4GZ8

Mouse Semaphorin 3A, domains Sema-PSI-IG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Semaphorin-3A	polymer	667	72416.1	2	UniProt (O08665) Pfam (PF01403) In PDB	Mus musculus (mouse)	Semaphorin III, Sema III, Semaphorin-D, Sema D
2	C	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
3	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	E	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G22573RC)
5	A, B	CALCIUM ION	non-polymer		40.1	5	Chemie (CA)
6	A, B	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
7	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A, B: 21 - 569 (UniProt: O08665)

PDB	External Database	Details
Glu 18	-	expression tag
Thr 19	-	expression tag
Gly 20	-	expression tag
Val 475	Ile 475	SEE REMARK 999
Ala 551	Arg 551	engineered mutation
Ala 555	Arg 555	engineered mutation

A, B: 570 - 684 (PDB: 4GZ8)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	144832.2
Branched	Number of molecules	3
	Total formula weight	1921.8
Non-Polymers*	Number of molecules	8
	Total formula weight	539.7
All*	Total formula weight	147293.6

*Water molecules are not included.