4GZ8
Mouse Semaphorin 3A, domains Sema-PSI-IG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Semaphorin-3A | polymer | 667 | 72416.1 | 2 | UniProt (O08665) Pfam (PF01403) | Mus musculus (mouse) | Semaphorin III, Sema III, Semaphorin-D, Sema D |
| 2 | C (C) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 3 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E (E) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 5 | F, G, H, J, K (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 6 | I, M (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 7 | L (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A, B: 21 - 569 (UniProt: O08665)
A, B: 570 - 684 (PDB: 4GZ8)
| PDB | External Database | Details |
|---|---|---|
| Glu 18 | - | expression tag |
| Thr 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Val 475 | Ile 475 | SEE REMARK 999 |
| Ala 551 | Arg 551 | engineered mutation |
| Ala 555 | Arg 555 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 144832.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1921.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 539.7 | |
| All* | Total formula weight | 147293.6 |
