4GX8

Crystal structure of a DNA polymerase III alpha-epsilon chimera

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	DNA polymerase III subunit epsilon,DNA polymerase III subunit alpha	polymer	315	34628.2	4	UniProt (P03007) UniProt (P10443) Pfam (PF02811)	Escherichia coli
2	E, F, G, H (A, B, C, D)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
3	I, J, K, L (A, B, C, D)	water	water		18.0	1128	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 36 (UniProt: P03007)

PDB	External Database	Details
Met 1	-	initiating methionine
Thr 37	-	linker
Arg 38	-	linker
Glu 39	-	linker
Ser 40	-	linker
Gly 41	-	linker
Ser 42	-	linker
Ile 43	-	linker
Gly 44	-	linker
Ser 45	-	linker

A, B, C, D: 46 - 315 (UniProt: P10443)

PDB	External Database	Details
Pro 66	Leu 21	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	138513.0
Non-Polymers*	Number of molecules	4
	Total formula weight	141.8
All*	Total formula weight	138654.8

*Water molecules are not included.