4GWS
Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fructose-1,6-bisphosphatase 1 | polymer | 337 | 36848.4 | 2 | UniProt (P00636) Pfam (PF00316) Pfam (PF18913) | Sus scrofa (pig) | FBPase 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 |
| 2 | C, G (A, B) | 6-O-phosphono-beta-D-fructofuranose | non-polymer | 260.1 | 2 | Chemie (F6P) | |||
| 3 | D, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | E, I (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (34768) PubChem (83862) PubChem (40467049) PubChem (40469468) PubChem (446048) PubChem (44348067) PubChem (45358029) PubChem (40459109) PubChem (515384) PubChem (46874558) PubChem (638042) PubChem (46875232) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (5316444) PubChem (5742864) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (12163610) PubChem (12358355) PubChem (92144436) PubChem (122197642) PubChem (12358354) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 5 | F, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) PubChem (1061) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 337 (UniProt: P00636)
| PDB | External Database | Details |
|---|---|---|
| His 45 | Ser 46 | engineered mutation |
| Arg 46 | Thr 47 | engineered mutation |
| Tyr 186 | Leu 187 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73696.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1453.3 | |
| All* | Total formula weight | 75150.0 |
