4GWS
Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fructose-1,6-bisphosphatase 1 | polymer | 337 | 36848.4 | 2 | UniProt (P00636) Pfam (PF00316) Pfam (PF18913) | Sus scrofa (pig) | FBPase 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 |
| 2 | C, G (A, B) | 6-O-phosphono-beta-D-fructofuranose | non-polymer | 260.1 | 2 | Chemie (F6P) | |||
| 3 | D, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, I (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 5 | F, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 337 (UniProt: P00636)
| PDB | External Database | Details |
|---|---|---|
| His 45 | Ser 46 | engineered mutation |
| Arg 46 | Thr 47 | engineered mutation |
| Tyr 186 | Leu 187 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73696.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1453.3 | |
| All* | Total formula weight | 75150.0 |
