Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

4GWQ

Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA Polymerase II Rpb1 subunit

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		Mediator of RNA polymerase II transcription subunit 11polymer11513324.21UniProt (Q99278)
Pfam (PF10280)		Saccharomyces cerevisiae (Baker's yeast)Mediator complex subunit 11
2B
(B)		Mediator of RNA polymerase II transcription subunit 17polymer68778582.81UniProt (P32569)
Pfam (PF10156)		Saccharomyces cerevisiae S288c (Baker's yeast)Mediator complex subunit 17, Suppressor of RNA polymerase B 4
3C
(C)		Mediator of RNA polymerase II transcription subunit 8polymer40745930.01UniProt (P38304)
Pfam (PF10232)		Saccharomyces cerevisiae (Baker's yeast)Mediator complex subunit 8
4D
(D)		Mediator of RNA polymerase II transcription subunit 22polymer12113875.71UniProt (P32570)
Pfam (PF06179)		Saccharomyces cerevisiae (Baker's yeast)Mediator complex subunit 22, Suppressor of RNA polymerase B 6
5E
(E)		Mediator of RNA polymerase II transcription subunit 18polymer30734316.51UniProt (P32585)
Pfam (PF09637)		Saccharomyces cerevisiae (Baker's yeast)Mediator complex subunit 18, Suppressor of RNA polymerase B 5
6F
(F)		Mediator of RNA polymerase II transcription subunit 20polymer21022918.11UniProt (P34162)
Pfam (PF08612)		Saccharomyces cerevisiae (Baker's yeast)Hyper-recombination suppressor protein 2, Mediator complex subunit 20, Suppressor of RNA polymerase B 2
7G
(G)		Mediator of RNA polymerase II transcription subunit 6polymer29532844.71UniProt (P38782)
Pfam (PF04934)		Saccharomyces cerevisiae S288c (Baker's yeast)Mediator complex subunit 6
8H
(H)		DNA-directed RNA polymerase II subunit RPB1polymer353616.71UniProt (P04050)
Pfam (PF05001)		Saccharomyces cerevisiaeRNA polymerase II subunit 1, RNA polymerase II subunit B1, DNA-directed RNA polymerase III largest subunit, RNA polymerase II subunit B220
Sequence modifications
C: 1 - 223 (UniProt: P38304)
PDBExternal DatabaseDetails
Ser 224-expression tag
Met 225-expression tag
Glu 226-expression tag
Lys 227-expression tag
Arg 228-expression tag
Arg 229-expression tag
Trp 230-expression tag
Lys 231-expression tag
Lys 232-expression tag
Asn 233-expression tag
Phe 234-expression tag
Ile 235-expression tag
Ala 236-expression tag
Val 237-expression tag
Ser 238-expression tag
Ala 239-expression tag
Ala 240-expression tag
Asn 241-expression tag
Arg 242-expression tag
Phe 243-expression tag
Lys 244-expression tag
Lys 245-expression tag
Ile 246-expression tag
Ser 247-expression tag
Ser 248-expression tag
Ser 249-expression tag
Gly 250-expression tag
Ala 251-expression tag
Leu 252-expression tag
Asp 253-expression tag
Tyr 254-expression tag
Asp 255-expression tag
Ile 256-expression tag
Pro 257-expression tag
Thr 258-expression tag
Thr 259-expression tag
Ala 260-expression tag
Ser 261-expression tag
Glu 262-expression tag
Asn 263-expression tag
Leu 264-expression tag
Tyr 265-expression tag
Phe 266-expression tag
Gln 267-expression tag
Gly 268-expression tag
Glu 269-expression tag
Leu 270-expression tag
Lys 271-expression tag
Thr 272-expression tag
Ala 273-expression tag
Ala 274-expression tag
Leu 275-expression tag
Ala 276-expression tag
Gln 277-expression tag
His 278-expression tag
Asp 279-expression tag
Glu 280-expression tag
Ala 281-expression tag
Val 282-expression tag
Asp 283-expression tag
Asn 284-expression tag
Lys 285-expression tag
Phe 286-expression tag
Asn 287-expression tag
Lys 288-expression tag
Glu 289-expression tag
Gln 290-expression tag
Gln 291-expression tag
Asn 292-expression tag
Ala 293-expression tag
Phe 294-expression tag
Tyr 295-expression tag
Glu 296-expression tag
Ile 297-expression tag
Leu 298-expression tag
His 299-expression tag
Leu 300-expression tag
Pro 301-expression tag
Asn 302-expression tag
Leu 303-expression tag
Asn 304-expression tag
Glu 305-expression tag
Glu 306-expression tag
Gln 307-expression tag
Arg 308-expression tag
Asn 309-expression tag
Ala 310-expression tag
Phe 311-expression tag
Ile 312-expression tag
Gln 313-expression tag
Ser 314-expression tag
Leu 315-expression tag
Lys 316-expression tag
Asp 317-expression tag
Asp 318-expression tag
Pro 319-expression tag
Ser 320-expression tag
Gln 321-expression tag
Ser 322-expression tag
Ala 323-expression tag
Asn 324-expression tag
Leu 325-expression tag
Leu 326-expression tag
Ala 327-expression tag
Glu 328-expression tag
Ala 329-expression tag
Lys 330-expression tag
Lys 331-expression tag
Leu 332-expression tag
Asn 333-expression tag
Asp 334-expression tag
Ala 335-expression tag
Gln 336-expression tag
Ala 337-expression tag
Pro 338-expression tag
Lys 339-expression tag
Val 340-expression tag
Asp 341-expression tag
Asn 342-expression tag
Lys 343-expression tag
Phe 344-expression tag
Asn 345-expression tag
Lys 346-expression tag
Glu 347-expression tag
Gln 348-expression tag
Gln 349-expression tag
Asn 350-expression tag
Ala 351-expression tag
Phe 352-expression tag
Tyr 353-expression tag
Glu 354-expression tag
Ile 355-expression tag
Leu 356-expression tag
His 357-expression tag
Leu 358-expression tag
Pro 359-expression tag
Asn 360-expression tag
Leu 361-expression tag
Asn 362-expression tag
Glu 363-expression tag
Glu 364-expression tag
Gln 365-expression tag
Arg 366-expression tag
Asn 367-expression tag
Ala 368-expression tag
Phe 369-expression tag
Ile 370-expression tag
Gln 371-expression tag
Ser 372-expression tag
Leu 373-expression tag
Lys 374-expression tag
Asp 375-expression tag
Asp 376-expression tag
Pro 377-expression tag
Ser 378-expression tag
Gln 379-expression tag
Ser 380-expression tag
Ala 381-expression tag
Asn 382-expression tag
Leu 383-expression tag
Leu 384-expression tag
Ala 385-expression tag
Glu 386-expression tag
Ala 387-expression tag
Lys 388-expression tag
Lys 389-expression tag
Leu 390-expression tag
Asn 391-expression tag
Gly 392-expression tag
Ala 393-expression tag
Gln 394-expression tag
Ala 395-expression tag
Pro 396-expression tag
Lys 397-expression tag
Val 398-expression tag
Asp 399-expression tag
Ala 400-expression tag
Asn 401-expression tag
Ser 402-expression tag
Ala 403-expression tag
Gly 404-expression tag
Lys 405-expression tag
Ser 406-expression tag
Thr 407-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight245408.8
All*Total formula weight245408.8
*Water molecules are not included.

237423

PDB entries from 2025-06-11

PDB statisticsPDBj update infoContact PDBjnumon