4GUT
Crystal structure of LSD2-NPAC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific histone demethylase 1B | polymer | 776 | 87051.5 | 1 | UniProt (Q8NB78) Pfam (PF07496) Pfam (PF04433) Pfam (PF01593) | Homo sapiens (human) | LSD2, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2 |
| 2 | B (B) | Putative oxidoreductase GLYR1 | polymer | 124 | 13528.3 | 1 | UniProt (Q49A26) | Homo sapiens (human) | NPAC, 3-hydroxyisobutyrate dehydrogenase-like protein, Cytokine-like nuclear factor N-PAC, Glyoxylate reductase 1 homolog, Nuclear protein NP60, Nuclear protein of 60 kDa |
| 3 | C (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, G, H (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 6 | I (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 7 | J, K (A, B) | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence modifications
A: 51 - 822 (UniProt: Q8NB78)
B: 152 - 268 (UniProt: Q49A26)
| PDB | External Database | Details |
|---|---|---|
| Pro 47 | - | expression tag |
| Leu 48 | - | expression tag |
| Gly 49 | - | expression tag |
| Ser 50 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Pro 145 | - | expression tag |
| Leu 146 | - | expression tag |
| Gly 147 | - | expression tag |
| Ser 148 | - | expression tag |
| Pro 149 | - | expression tag |
| Glu 150 | - | expression tag |
| Phe 151 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100579.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1316.1 | |
| All* | Total formula weight | 101896.0 |
