4GU1

Crystal structure of LSD2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Lysine-specific histone demethylase 1B	polymer	784	88098.8	2	UniProt (Q8NB78) Pfam (PF07496) Pfam (PF04433) Pfam (PF01593) In PDB	Homo sapiens (human)	LSD2, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2
2	A, B	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	A, B	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
4	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5	A, B	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
6		water	water		18.0	23	Chemie (HOH)

Sequence modifications

A, B: 51 - 822 (UniProt: Q8NB78)

PDB	External Database	Details
Pro 39	-	expression tag
Leu 40	-	expression tag
Gly 41	-	expression tag
Ser 42	-	expression tag
Glu 43	-	expression tag
Phe 44	-	expression tag
Lys 45	-	expression tag
Gly 46	-	expression tag
Leu 47	-	expression tag
Arg 48	-	expression tag
Arg 49	-	expression tag
Arg 50	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	176197.6
Non-Polymers*	Number of molecules	14
	Total formula weight	2151.3
All*	Total formula weight	178349.0

*Water molecules are not included.