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4GU1

Crystal structure of LSD2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Lysine-specific histone demethylase 1Bpolymer78488098.82UniProt (Q8NB78)
Pfam (PF07496)
Pfam (PF04433)
Pfam (PF01593)
Homo sapiens (human)LSD2, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2
2C, J
(A, B)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.52Chemie (FAD)
3D, E, K, L
(A, B)
CHLORIDE IONnon-polymer35.54Chemie (CL)
4F, M
(A, B)
SODIUM IONnon-polymer23.02Chemie (NA)
5G, H, I, N, O...
(A, B)
ZINC IONnon-polymer65.46Chemie (ZN)
6Q, R
(A, B)
waterwater18.023Chemie (HOH)
Sequence modifications
A, B: 51 - 822 (UniProt: Q8NB78)
PDBExternal DatabaseDetails
Pro 39-expression tag
Leu 40-expression tag
Gly 41-expression tag
Ser 42-expression tag
Glu 43-expression tag
Phe 44-expression tag
Lys 45-expression tag
Gly 46-expression tag
Leu 47-expression tag
Arg 48-expression tag
Arg 49-expression tag
Arg 50-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight176197.6
Non-Polymers*Number of molecules14
Total formula weight2151.3
All*Total formula weight178349.0
*Water molecules are not included.

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PDB entries from 2026-01-14

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