4GU0
Crystal structure of LSD2 with H3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Lysine-specific histone demethylase 1B | polymer | 776 | 87051.5 | 4 | UniProt (Q8NB78) Pfam (PF07496) Pfam (PF04433) Pfam (PF01593) In PDB | Homo sapiens (human) | LSD2, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2 |
| 2 | E, F | Histone H3.3 | polymer | 26 | 2793.3 | 2 | UniProt (P84243) In PDB | Homo sapiens | |
| 3 | A, B, C, D | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 5 | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 51 - 822 (UniProt: Q8NB78)
E, F: 1 - 26 (UniProt: P84243)
| PDB | External Database | Details |
|---|---|---|
| Pro 47 | - | expression tag |
| Leu 48 | - | expression tag |
| Gly 49 | - | expression tag |
| Ser 50 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 4 | Lys 5 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 353792.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3927.1 | |
| All* | Total formula weight | 357719.9 |
