4GTC

T. Maritima FDTS (E144R mutant) plus FAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Thymidylate synthase thyX	polymer	232	27531.8	4	UniProt (Q9WYT0) Pfam (PF02511)	Thermotoga maritima	TS, TSase
2	E, F, G, H (A, B, C, D)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	4	Chemie (FAD)
3	I, J, K, L (A, B, C, D)	water	water		18.0	265	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 220 (UniProt: Q9WYT0)

PDB	External Database	Details
Met -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Asp -8	-	expression tag
Lys -7	-	expression tag
Ile -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Arg 144	Glu 144	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110127.0
Non-Polymers*	Number of molecules	4
	Total formula weight	3142.2
All*	Total formula weight	113269.2

*Water molecules are not included.