4GSQ
Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Probable conserved lipoprotein LPPS | polymer | 287 | 31280.7 | 1 | UniProt (O53223) Pfam (PF17964) Pfam (PF03734) | Mycobacterium tuberculosis | LdtMt2 |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A: 131 - 408 (UniProt: O53223)
| PDB | External Database | Details |
|---|---|---|
| Met 130 | - | expression tag |
| Leu 409 | - | expression tag |
| Glu 410 | - | expression tag |
| His 411 | - | expression tag |
| His 412 | - | expression tag |
| His 413 | - | expression tag |
| His 414 | - | expression tag |
| His 415 | - | expression tag |
| His 416 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31280.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 132.2 | |
| All* | Total formula weight | 31412.9 |
