4GRZ
Crystal structure of SHP1 catalytic domain with PO4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 6 | polymer | 288 | 32918.1 | 1 | UniProt (P29350) Pfam (PF00102) | Homo sapiens (human) | Hematopoietic cell protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1C, PTP-1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1 |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | water | water | 18.0 | 391 | Chemie (HOH) |
Sequence modifications
A: 243 - 528 (UniProt: P29350)
| PDB | External Database | Details |
|---|---|---|
| Gly 241 | - | expression tag |
| Ser 242 | - | expression tag |
| Ser 453 | Cys 453 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32918.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 33013.1 |
