4GRP
Crystallographic and biological characterization of N- and C- terminus mutants of human MIF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 118 | 12639.4 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (human) | MIF, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase |
| 2 | D, E, F, H, I (A, B, C) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | G, J (B, C) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | K, L, M (A, B, C) | water | water | 18.0 | 428 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 118 (UniProt: P14174)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | - | insertion |
| Ala 3 | - | insertion |
| Ala 4 | - | insertion |
| Ala 5 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37918.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 551.2 | |
| All* | Total formula weight | 38469.3 |
