4GRK
Crystal Structure of C-lobe of Bovine lactoferrin Complexed with ketorolac at 1.68 A Resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Lactotransferrin | polymer | 335 | 36622.3 | 1 | UniProt (P24627) Pfam (PF00405) In PDB | Bos taurus (bovine) | Lactoferrin, Lactoferricin-B, Lfcin-B |
2 | B | C-terminal peptide from Lactotransferrin | polymer | 6 | 652.8 | 1 | UniProt (P24627) In PDB | Bos taurus (bovine) | |
3 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
4 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
6 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
7 | A | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
8 | A | CARBONATE ION | non-polymer | 60.0 | 1 | Chemie (CO3) | |||
9 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
10 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
11 | A | (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid | non-polymer | 255.3 | 1 | Chemie (KTR) | |||
12 | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence modifications
A: 342 - 676 (UniProt: P24627)
PDB | External Database | Details |
---|---|---|
Lys 565 | Asn 584 | SEE REMARK 999 |
Glu 608 | Lys 627 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 37275.1 | |
Branched | Number of molecules | 2 |
Total formula weight | 1010.9 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1003.4 | |
All* | Total formula weight | 39289.4 |