4GQ0
Crystal structure of AKR1B10 complexed with NADP+ and Caffeic acid phenethyl ester
Replaces: 3V9QEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aldo-keto reductase family 1 member B10 | polymer | 318 | 36297.8 | 1 | UniProt (O60218) Pfam (PF00248) UniProt (by SIFTS) (P15121) | Homo sapiens (human) | ARL-1, Aldose reductase-like, Aldose reductase-related protein, ARP, hARP, Small intestine reductase, SI reductase |
| 2 | B (A) | 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate | non-polymer | 284.3 | 1 | Chemie (QAP) | |||
| 3 | C (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | D (A) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 1 - 316 (UniProt: O60218)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Asp 313 | Asn 313 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36297.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1027.7 | |
| All* | Total formula weight | 37325.5 |
