4GP2

Crystal structure of ISOPRENOID SYNTHASE A3MSH1 (TARGET EFI-501992) from pyrobaculum calidifontis complexed with DMAPP and Magnesium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Polyprenyl synthetase	polymer	358	40151.8	2	UniProt (A3MSH1) Pfam (PF00348)	Pyrobaculum calidifontis
2	C, D, G, H, I... (A, B)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
3	E, F, K, L (A, B)	DIMETHYLALLYL DIPHOSPHATE	non-polymer		246.1	4	Chemie (DMA)
4	M, N (A, B)	water	water		18.0	255	Chemie (HOH)

Sequence modifications

A, B: 3 - 336 (UniProt: A3MSH1)

PDB	External Database	Details
Met 1	-	expression tag
Val 2	-	expression tag
Ala 337	-	expression tag
Glu 338	-	expression tag
Asn 339	-	expression tag
Leu 340	-	expression tag
Tyr 341	-	expression tag
Phe 342	-	expression tag
Gln 343	-	expression tag
Ser 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag
His 350	-	expression tag
Trp 351	-	expression tag
Ser 352	-	expression tag
His 353	-	expression tag
Pro 354	-	expression tag
Gln 355	-	expression tag
Phe 356	-	expression tag
Glu 357	-	expression tag
Lys 358	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80303.7
Non-Polymers*	Number of molecules	10
	Total formula weight	1130.2
All*	Total formula weight	81433.9

*Water molecules are not included.